Clearing Assisted Scattering Tomography (CAST)

CAST leverages tissue clearing to tailor the scattering properties of tissue and enable label-free volumetric optical imaging at high speed.

NESBO 2019

CBORT to host Northeast Symposium on Biomedical Optics 2019

NESBO is an annual event aimed at bringing together junior researchers in Biomedical Optics from across the greater Northeast to stimulate scientific discussion and promote collaboration within the community. It is a great opportunity to interact with other young researchers in a relaxed atmosphere. This one-day symposium will be held on October 15th, 2019 at MIT.


Intravascular Polarimetry in Patients with Coronary Artery Disease

Otsuka et al. investigated the polarization properties of atherosclerotic plaques in patients with coronary artery disease. Using a modified optical frequency domain imaging (OFDI) console along with recently developed image reconstruction methods enabled measurement of polarization properties of the coronary arterial wall through standard intravascular OFDI catheters. This first-in-human pilot study of intravascular polarimetry demonstrated that culprit lesions of patients with acute coronary syndrome or plaque rupture exhibit a lower birefringence than those of patients presenting with stable angina pectoris. Polarization features also differed among different morphological plaque subtypes. Intravascular polarimetry may open new avenues for studying plaque composition and detecting high-risk patients.